:root{--cyan:#2563eb;--purple:#8B5CF6;--t1:#0f172a;--t2:#475569;--card:#ffffff;--bdr:rgba(37,99,235,.1)}
body{background:#f8fafc;color:#0f172a;font-family:-apple-system,BlinkMacSystemFont,'PingFang SC','Microsoft YaHei',sans-serif;margin:0}
.fg{margin-bottom:16px}.fg label{display:block;font-size:.88rem;color:var(--t2);margin-bottom:6px;font-weight:500}
.fg textarea{padding:12px 14px;background:rgba(10,14,23,.8);border:1px solid rgba(48,54,61,.5);border-radius:10px;color:var(--t1);font-size:.9rem;font-family:monospace;box-sizing:border-box;width:100%;resize:vertical;min-height:120px;transition:border-color .2s}
.fg select{padding:12px 14px;background:rgba(10,14,23,.8);border:1px solid rgba(48,54,61,.5);border-radius:10px;color:var(--t1);font-size:.9rem;font-family:monospace;box-sizing:border-box;width:100%;transition:border-color .2s}
.req{color:#f87171}.ts{display:inline-flex;align-items:center;gap:8px;padding:12px 32px;background:var(--cyan);color:#fff;border:none;border-radius:10px;font-size:.95rem;font-weight:600;cursor:pointer}.ts:hover{box-shadow:0 0 24px rgba(37,99,235,.25)}
.tr{padding:12px 24px;background:transparent;color:var(--t2);border:1px solid rgba(48,54,61,.5);border-radius:10px;font-size:.9rem;cursor:pointer}
@keyframes spin{to{transform:rotate(360deg)}}
/* 统计对比卡片 */
.stat-row{display:flex;gap:12px;flex-wrap:wrap;margin-bottom:16px}
.stat-tile{flex:1;min-width:140px;background:rgba(37,99,235,.04);border:1px solid rgba(37,99,235,.1);border-radius:10px;padding:14px 16px}
.stat-tile .sl{font-size:.72rem;color:var(--t2);margin-bottom:6px}
.stat-tile .sv{font-size:1.15rem;font-weight:700;color:var(--t1)}
.stat-tile .delta{font-size:.74rem;margin-top:4px}
/* SnapGene 风格序列显示 */
.seq-box{background:#0b1220;border:1px solid rgba(48,54,61,.5);border-radius:10px;padding:16px;overflow-x:auto}
.seq-line{font-family:ui-monospace,SFMono-Regular,'Cascadia Mono',Consolas,monospace;font-size:.86rem;line-height:1.9;white-space:pre;color:#e2e8f0}
.seq-pos{display:inline-block;min-width:3.5em;color:#64748b;font-size:.72rem;text-align:right;margin-right:1em;user-select:none}
.seq-line .grp{margin-right:.8em}
.toolbar{display:flex;gap:10px;flex-wrap:wrap;margin-bottom:16px}
.btn-sm{display:inline-flex;align-items:center;gap:6px;padding:8px 18px;border-radius:8px;font-size:.85rem;font-weight:600;cursor:pointer;border:1px solid rgba(48,54,61,.5);background:transparent;color:var(--t2)}
.btn-sm.primary{background:var(--cyan);color:#fff;border-color:transparent}
.warn-box{margin-top:12px;padding:10px 14px;background:rgba(251,191,36,.08);border:1px solid rgba(251,191,36,.3);border-radius:8px;font-size:.8rem;color:#92400e;line-height:1.7}
.result-card{background:var(--card);border:1px solid var(--bdr);border-radius:12px;padding:20px;margin-bottom:20px}
.result-card h4{color:#0f172a;margin:0 0 12px}
@media(max-width:768px){.main-grid{grid-template-columns:1fr!important}}